Theme 01
Joint preservation before replacement
The core organising question across two decades of work.
A clinical and research focus on the realistic window where the joint can still be preserved, biologically supported or repaired before replacement becomes the default. Threads through the cartilage, meniscus, ligament and recovery work, and underpins the Preserve to Replace decision pathway used in clinical practice.
Theme 02
Cartilage regeneration
ChondroFiller, STACi and the single-stage cartilage repair question.
Articular cartilage repair, scaffold-augmented techniques, ChondroFiller (CFI / CFI+ / CFI++) and the single-stage Tissue-engineered Autologous Cartilage Implantation (STACi) line. The research record interrogates patient selection, evidence boundaries, mid-term outcomes and the line between focal defect repair and advanced osteoarthritis.
Theme 03
ACL repair and ligament preservation
STARR augmented repair and the case against default reconstruction.
Single Treatment ACL Regenerative Repair (STARR), BEAR-style augmented repair and the wider preservation-first framing of acute ACL injury. The research record interrogates ligament preservation evidence, MPFL stability work and the return-to-sport pathway behind preserved-ligament surgery.
Related projects:ACL.Repair Theme 04
Meniscus preservation
Meniscus matters more than the patient is told.
Meniscus repair vs meniscectomy, root tear management and combined cartilage-meniscus work. Recurrent question across the medico-legal record too, where the long-term arthritis risk associated with meniscectomy is the load-bearing causation point.
Related projects:Meniscus.Repair Theme 05
Hip-preserving surgical approaches
SPAIRE and the soft-tissue discipline behind a good hip replacement.
Hip arthroplasty research with a focus on soft-tissue preservation: SPAIRE (Spare Piriformis And Internus, Repair Externus), short femoral stems, planning for leg-length equality and offset, and the materials and bearing-surface debates that frame implant choice. The book chapter and lecture record run alongside.
Theme 06
Biological augmentation and orthobiologics
Used precisely, never as a marketing category.
Polyacrylamide hydrogel (Arthrosamid), PRP, PRF, microfragmented adipose tissue (mFAT) and corticosteroid evidence. The published record spans the protocol-development work behind Professor Lee’s Arthrosamid practice, the autologous biologic options and the boundary between mechanical and biological injection effects.
Theme 07
Imaging, motion analysis and AI
Movement medicine, made measurable.
Markerless motion capture, MAI Motion biomechanical biomarkers, AI-driven MRI interpretation (onMRI) and explainable AI in healthcare. The published work supports the device-development work behind MAI Motion and onMRI and frames the case for AI as a clinical-decision support tool rather than a black box.
Theme 08
Recovery and rehabilitation optimisation
Recovery is part of the operation, not after it.
Peri-operative nutrition, blood-flow restriction training, unloading knee braces, the recovery-as-system framing that runs through the RegenPhD work. The published record connects the clinical pathway with the recovery layer that determines whether the clinical input becomes a result.
Theme 09
Consent and clinical pathway design
Digital consent as a research problem, not a paperwork problem.
Digital consent, cost-consequence analysis and informed-consent research. Connected to the Consent Plus work that won The Health Foundation Innovation Award. The pathway-design strand interrogates how the consent conversation, the decision pathway and the recovery plan fit together.
Theme 10
Knee replacement decision-making
Partial vs total, alignment philosophy, patellofemoral discipline.
Knee arthroplasty research with the same preservation discipline as the cartilage and meniscus work: partial vs total decisions, alignment philosophy, patellofemoral compartment management and the soft-tissue balancing that drives functional outcome. Includes TWIS-TKR development.
Theme 11
Regenerative orthopaedics, end-to-end
The synthesis of the themes above into a clinical discipline.
Microfragmented adipose tissue, Actovegin and biological augmentation across the musculoskeletal system. The synthesis question across all of the work above: how the regenerative-orthopaedics field actually advances, what survives translation from the bench and what does not. Underpins the Springer Nature Editor-in-Chief reference textbook.